Blisters may develop from diseases that cause your body to attack
your own skin (autoimmune diseases), such as:
Pemphigus, an uncommon,
sometimes fatal disease. Blisters of varying sizes break out on the skin, the
lining of the mouth, the vagina or penis, and other mucous membranes. Treatment
includes medicine to suppress the
immune system and, sometimes, a plasma exchange
Bullous pemphigoid, a less dangerous disease than pemphigus. Blisters are itchy,
hard, and tight, and the skin between the blisters is red and may be swollen.
Unlike in pemphigus, blisters do not form in the mouth. Treatment involves
medicine to suppress the immune system.
Dermatitis herpetiformis, a chronic inflammatory disease that
may be caused by a sensitivity or allergy to
gluten. Clusters of small blisters and swellings that itch and burn like hives break out on the skin of the elbows, knees,
buttocks, lower back, and back of the head. Occasionally blisters form on the
face and neck. Treatment includes taking medicine and removing all foods that
contain wheat, rye, barley, and oats from your diet.