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Brand NameGeneric NameChemical Name
Faslodexfulvestrant

Fulvestrant is available as an intramuscular (IM) injection.

Fulvestrant is called an antiestrogen medicine. This means that it blocks the effect of estrogen in the body. It is only used for postmenopausal women who have been diagnosed with estrogen receptor-positive (ER+) breast cancer.

Fulvestrant is used to treat estrogen receptor-positive (ER+) metastatic breast cancer in postmenopausal women when other hormonal therapies, such as tamoxifen, have stopped working.

Fulvestrant is as effective as aromatase inhibitors, such as anastrozole (Arimidex), in the treatment of women for metastatic breast cancer when other hormonal therapies, such as tamoxifen, have stopped working. It only works for postmenopausal women who have been diagnosed with estrogen receptor-positive (ER+) breast cancer.

Most women do not have problems with side effects while taking fulvestrant. When side effects happen, they are typically mild and may include:

  • Nausea or vomiting.
  • Constipation or diarrhea.
  • Abdominal (belly) pain.
  • Headache.
  • Back pain.
  • Hot flashes.
  • Sore throat.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

Fulvestrant should be given only under the supervision of a medical oncologist. It is approved for use after menopause.

Do not take this medicine if you are or may be pregnant. Do not breast-feed while you are taking this medicine.

Complete the new medication information form (PDF) (What is a PDF document?) to help you understand this medication.


By: Healthwise Staff Last Revised: August 14, 2013
Medical Review: Sarah Marshall, MD - Family Medicine
Douglas A. Stewart, MD - Medical Oncology

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