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digoxin (oral)

digoxin (oral)

Pronunciation: di JOX in

Brand: Digitek, Lanoxicaps, Lanoxin

Digitek 0.125 mg

round, yellow, imprinted with B 145

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Digitek 0.25 mg-MYL

round, white, imprinted with B 146

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Digoxin 0.125 mg-LAN

round, yellow, imprinted with JSP 544

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Digoxin 0.25 mg-LAN

round, white, imprinted with JSP 545

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Digoxin 50 mcg Elix-ROX

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Lanoxicaps 0.1 mg

clear/yellow, imprinted with B2C

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Lanoxin 0.125 mg

round, yellow, imprinted with LANOXIN Y3B

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Lanoxin 0.25 mg

round, white, imprinted with LANOXIN X3A

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What is the most important information I should know about digoxin?

Multum donot

You should not use this medication if you are allergic to digoxin, or if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart).

Before using digoxin, tell your doctor if you have certain heart conditions, especially "AV block" (unless you have a pacemaker), or a recent history of heart attack. Also tell your doctor if you have kidney disease, a thyroid disorder, an electrolyte imbalance (such as low levels of calcium, potassium, or magnesium in your blood), or if you are malnourished or have recently been sick with vomiting or diarrhea.

Keep taking digoxin as directed, even if you feel well. Get your prescription refilled before you run out of medicine completely.

Multum donot

Do not stop taking digoxin without first talking to your doctor. Stopping suddenly may make your condition worse.

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Digoxin overdose can occur more easily if you are dehydrated.

There are many other drugs that can interact with digoxin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

What is digoxin?

Digoxin is derived from the leaves of a digitalis plant. Digoxin helps make the heart beat stronger and with a more regular rhythm.

Digoxin is used to treat heart failure.

Digoxin is also used to treat atrial fibrillation, a heart rhythm disorder of the atria (the upper chambers of the heart that allow blood to flow into the heart).

Digoxin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking digoxin?

Multum donot

You should not use this medication if you are allergic to digoxin, or if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart).

To make sure you can safely take digoxin, tell your doctor if you have any of these other conditions:

  • certain serious heart conditions, especially "AV block" (unless you have a pacemaker);
  • a recent history of heart attack;
  • kidney disease;
  • a thyroid disorder;
  • an electrolyte imbalance (such as low levels of calcium, potassium, or magnesium in your blood); or
  • if you are malnourished or have recently been sick with vomiting or diarrhea.
Multum nopreg

FDA pregnancy category C. It is not known whether digoxin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Multum nobrfeed

Digoxin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more likely to have side effects from digoxin.

How should I take digoxin?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Multum water

Take digoxin with a full glass of water.

Try to take the medication at the same time every day.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

To be sure this medication is not causing harmful effects, your blood may need to be tested on a regular basis. Your kidney function may also need to be tested. Do not miss any scheduled appointments.

Keep taking digoxin as directed, even if you feel well. Get your prescription refilled before you run out of medicine completely.

Multum donot

Do not stop taking digoxin without first talking to your doctor. Stopping suddenly may make your condition worse.

Multum rt

Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If your next dose is less than 12 hours away, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of digoxin can be fatal.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

What should I avoid while taking digoxin?

Multum nosun

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Digoxin overdose can occur more easily if you are dehydrated.

What are the possible side effects of digoxin?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Call your doctor at once if you have a serious side effect such as:

  • fast, slow, or uneven heart rate;
  • bloody or black, tarry stools;
  • blurred vision, yellowed vision; or
  • confusion, hallucinations, unusual thoughts or behavior.

Less serious side effects may include:

  • nausea, vomiting, diarrhea, loss of appetite;
  • feeling weak or dizzy;
  • headache, anxiety, depression;
  • enlarged breasts in men; or
  • mild skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect digoxin?

Many drugs can interact with digoxin. Below is just a partial list. Tell your doctor if you are using:

  • an antacid, or Kaopectate;
  • alprazolam (Xanax);
  • cancer medications;
  • clonidine (Catapres);
  • supplements or medications that contain calcium;
  • a diuretic (water pill), such as spironolactone (Aldactone, Aldactazide);
  • amphotericin B (Fungizone, AmBisome, Abelcet);
  • cholestyramine (Questran, Prevalite);
  • epinephrine (EpiPen);
  • indomethacin (Indocin);
  • isoproterenol (Isuprel);
  • itraconazole (Sporanox);
  • levothyroxine (Synthroid, Levothroid, and others);
  • metoclopramide (Reglan);
  • neomycin (Mycifradin, Neo-Fradin, Neo-Tab);
  • rifampin (Rifadin, Rifater, Rifamate);
  • St. John's wort;
  • sulfasalazine (Azulfidine); or
  • an antibiotic such as erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), clarithromycin (Biaxin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap);
  • heart or blood pressure medicine such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide), carvedilol (Coreg), diltiazem (Cardizem, Cartia, Dilacor, Diltia, Diltzac, Taztia, Tiazac), metoprolol (Dutoprol, Lopressor, Toprol), nebivolol (Bystolic), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan, Tarka), and others;
  • decongestant cold or allergy medicine, or nasal sprays such as Afrin, Duramist, Neo-Synephrine, Tysine Nasal, and others;
  • a heart rhythm medication such as amiodarone (Cordarone, Pacerone), propafenone (Rythmol), or quinidine (Quin-G); or
  • steroids such as prednisone, fluticasone (Advair), mometasone (Asmanex, Nasonex), dexamethasone (Decadron, Hexadrol) and others.

This list is not complete and there are many other drugs that can interact with digoxin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about digoxin.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2013 Cerner Multum, Inc. Version: 8.02. Revision date: 10/10/2012.

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