Update your browser or enable Javascript to view and use this site as designed.
sitagliptin

sitagliptin

Pronunciation: SI ta glip tin

Brand: Januvia

Januvia 25 mg

round, pink, imprinted with 221

Image of Januvia 25 mg
slide 1 of 3
    

Januvia 50 mg

round, beige, imprinted with 112

Image of Januvia 50 mg
slide 2 of 3
    

Januvia 100 mg

round, brown, imprinted with 277

Image of Januvia 100 mg
slide 3 of 3
    

What is the most important information I should know about sitagliptin?

Multum donot

Do not use this medicine if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

Multum calldoc

Sitagliptin can cause pancreatitis. Stop using this medicine and call your doctor at once if you have severe pain in your upper stomach spreading to your back, nausea and vomiting, and loss of appetite.

Multum emt

Sitagliptin can cause a serious allergic reaction. Get emergency medical help if you have a fever, sore throat, swelling or burning in your face, skin pain, and a skin rash that spreads and causes blistering and peeling.

What is sitagliptin?

Sitagliptin is an oral diabetes medicine that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating.

Sitagliptin is for people with type 2 diabetes. Sitagliptin is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes.

Sitagliptin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking sitagliptin?

Multum donot

Do not use this medicine if you are allergic to sitagliptin, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

To make sure sitagliptin is safe for you, tell your doctor if you have:

  • kidney disease (or if you are on dialysis); or
  • a history of pancreatitis.

FDA pregnancy category B. Sitagliptin is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Your name may need to be listed on a sitagliptin pregnancy registry when you start using this medicine.

Multum nobrfeed

It is not known whether sitagliptin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Multum nochild

Do not give this medication to anyone under 18 years old without medical advice.

How should I take sitagliptin?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You may take this medicine with or without food. Follow your doctor's instructions.

Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office. Visit your doctor regularly.

Multum dizzy

Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, pale skin, irritability, dizziness, feeling shaky, or trouble concentrating.

Keep a source of sugar with you in case you have low blood sugar. Sugar sources include fruit juice, hard candy, crackers, raisins, and non-diet soda. Be sure your family and close friends know how to help you in an emergency. If you have severe hypoglycemia and cannot eat or drink, use a glucagon injection. Your doctor can prescribe a glucagon emergency injection kit and tell you how to use it.

Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

Multum donot

Check your blood sugar carefully during times of stress, travel, illness, surgery or medical emergency, vigorous exercise, or if you drink alcohol or skip meals. These things can affect your glucose levels and your dose needs may also change. Do not change your medication dose or schedule without your doctor's advice.

Sitagliptin is only part of a complete program of treatment that also includes diet, exercise, weight control, and possibly other medications. It is important to use this medicine regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Multum rt

Store sitagliptin at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).

What should I avoid while taking sitagliptin?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of sitagliptin?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum calldoc

Stop using sitagliptin and call your doctor at once if you have:

  • pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, fast heart rate;
  • little or no urinating;
  • swelling, weight gain, feeling short of breath; or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include:

  • runny or stuffy nose, sore throat;
  • headache, back pain, joint or muscle pain; or
  • nausea, stomach pain, diarrhea, constipation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect sitagliptin?

Multum emt

Using certain medicines can make it harder for you to tell when you have low blood sugar. Tell your doctor if you use albuterol, clonidine, reserpine, or a beta-blocker (atenolol, metoprolol, propranolol, and others).

Before you take sitagliptin, tell your doctor if you are also taking digoxin (Lanoxicaps, Lanoxin).

Although sitagliptin is not as likely to cause hypoglycemia (low blood sugar) as some other oral diabetes medications, tell your doctor if you are taking any other drugs that can potentially lower blood sugar, such as:

  • probenecid (Benemid);
  • nonsteroidal anti-inflammatory drugs (NSAIDs);
  • aspirin or other salicylates (including Pepto-Bismol);
  • a blood thinner (warfarin, Coumadin);
  • sulfa drugs (Bactrim, SMX-TMP, and others);
  • a monoamine oxidase inhibitor (MAOI); or
  • beta-blockers (Tenormin and others).
  • insulin or other oral diabetes medications.

This list is not complete. Other drugs may interact with sitagliptin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Your pharmacist can provide more information about sitagliptin.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2014 Cerner Multum, Inc. Version: 8.02. Revision date: 3/28/2013.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.
Healthwise
Help
Healthwise Index

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.