COPD (Chronic Obstructive Pulmonary Disease)

COPD (Chronic Obstructive Pulmonary Disease)

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Medications

Medicine for COPD is used to:

  • Reduce shortness of breath.
  • Control coughing and wheezing.
  • Prevent COPD flare-ups, also called exacerbations, or keep the flare-ups you do have from being life-threatening.

Most people with COPD find that medicines make breathing easier.

Some COPD medicines are used with devices called inhalers or nebulizers. Most doctors recommend using spacers Click here to see an illustration. with inhalers. It's important to learn how to use these devices correctly. Many people don't, so they don't get the full benefit from the medicine.

Medicine choices

  • Bronchodilators are used to open or relax your airways Click here to see an illustration. and help your shortness of breath.
    • Short-acting bronchodilators ease your symptoms. They are considered a good first choice for treating stable COPD in a person whose symptoms come and go (intermittent symptoms). They include:
      • Anticholinergics (such as ipratropium).
      • Beta2-agonists (such as albuterol or levalbuterol).
      • A combination of the two (such as a combination of albuterol and ipratropium).
    • Long-acting bronchodilators help prevent breathing problems. They help people whose symptoms do not go away (persistent symptoms). They include:
      • Anticholinergics (such as tiotropium).
      • Beta2-agonists (such as arformoterol, formoterol, or salmeterol).
  • Phosphodiesterase-4 (PDE4) inhibitors are taken every day to help prevent COPD exacerbations. The only PDE4 inhibitor available is roflumilast (Daliresp).
  • Corticosteroids (such as prednisone) may be used in pill form to treat a COPD flare-up or in an inhaled form to prevent flare-ups. They are often used if you also have asthma.
  • The long-acting antimuscarinic medicine aclidinium (Tudorza Pressair), which is delivered through a dry powder inhaler, may be taken as a daily controller medicine to prevent COPD exacerbations.
  • Other medicines include methylxanthines, which generally are used for severe cases of COPD. They may have serious side effects, so they are not usually recommended.

Tips for using inhalers

The first time you use a bronchodilator, you may not notice much improvement in your symptoms. This doesn't always mean that the medicine won't help. Try the medicine for a while before you decide if it is working.

Metered-dose inhalers (MDIs) and nebulizers work equally well. MDIs are easier to carry. Nebulizers usually need to be plugged in.

Many people don't use their inhalers right, so they don't get the right amount of medicine. Ask your doctor or nurse to show you what to do. Read the instructions on the package carefully.

Click here to view an Actionset. Breathing Problems: Using a Metered-Dose Inhaler with or without a spacer
Click here to view an Actionset. Breathing Problems: Using a Dry Powder Inhaler
Author:
Healthwise Staff
Medical Review:
E. Gregory Thompson, MD - Internal Medicine
Ken Y. Yoneda, MD - Pulmonology
Last Updated:
October 16, 2012
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